Dean, College of Pharmacy

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Publications

Articles

51. Bishay, D.W., Che, C.T., Gonzalez, A., Pezzuto, J.M., Kinghorn, A.D., and Farnsworth, N.R. Further chemical constituents of Mitragyna inermis Stem Bark. Fitoterapia 59: 397-398, 1988.

52. Jayasuriya, H., McChesney, J.D., Swanson, S.M., and Pezzuto, J.M. Antimicrobial and cytotoxic activity of rottlerin-type compounds from Hypericum drummondii. J. Nat. Prod. 52: 325-331, 1989.

53. Jonathan, L.T., Che, C.-T., Pezzuto, J.M., Fong, H.H.S., and Farnsworth, N.R. 7-O-Methylhorminone and other cytotoxic diterpene quinones from Lepechinia bullata. J. Nat. Prod. 52: 571-575, 1989.

54. Choi, Y.-H., Hussain, R.A., Pezzuto, J.M., Kinghorn, A.S., and Morton, J.F. Abrusosides A-D, four novel sweet-tasting triterpene glycosides from the leaves of Abrus precatorius. J. Nat. Prod. 52: 1118-1127, 1989.

55. Kigodi, P.G.K., Blaskó, G., Thebtaranonth, Y., Pezzuto, J.M., and Cordell, G.A. A new limonoid from Azadirachta indica. Spectroscopic and biological investigation of nimbolide and 28-deoxynimbolide. J. Nat. Prod. 52: 1246-1251, 1989.

56. Blaskó, G., Shieh, H.-L., Pezzuto, J.M., and Cordell, G.A. Carbon-13 spectral assignment and evaluation of the cytotoxic potential of rotenone. J. Nat. Prod. 52: 1363-1366, 1989.

57. Braun, R.J., Pezzuto, J.M., Anderson, C.H., and Beattie, C.W. Estrous cycle status alters N-methyl-N-nitrosourea (NMU)-induced rat mammary tumor growth and regression. Cancer Lett. 48: 205-211, 1989.

58. Hamburger, M.O., Shieh, H.-L., Zhou, B.-N., Pezzuto, J.M., and Cordell, G.A. Pseudolaric acid B: NMR assignments, conformational analysis, and cytotoxicity. Magn. Reson. Chem. 27: 1025-1030, 1989.

59. Bavovada, R., Blaskó, G., Shieh, H.-L., Pezzuto, J.M., and Cordell, G.A. Spectral assignment and cytotoxicity of 22-hydroxytingenone from Glyptopetalum sclerocarpum. Planta Med. 56: 380-382, 1990.

60. Hussain, R.A., Lin, L.M., Proveda, L.M., Bordas, E., Chung, B.S., Pezzuto, J.M., Soejarto, D.D., and Kinghorn, A.D. Plant-derived sweetening agents: saccharide and polyol constituents of some sweet-tasting plants. J. Ethnopharmacol. 28: 103-115, 1990.

61. Hussain, R.A., Poveda, L.M., Pezzuto, J.M., Soejarto, D.D., and Kinghorn, A.D. Sweetening agents of plant origin: phenylpropanoid constituents of seven sweet-tasting plants. Econ. Bot. 44: 174-182, 1990.

62. Kardono, L.B.S., Tsauri, S., Padmawinata, K., Pezzuto, J.M., and Kinghorn, A.D. Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia. J. Nat. Prod. 53: 1447-1455, 1990.

63. Tan, G.T., Pezzuto, J.M., Kinghorn, A.D., and Hughes, S.H. Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. J. Nat. Prod. 54: 143-154, 1991.

64. Kaneda, N., Pezzuto, J.M., Soejarto, D.D., Kinghorn, A.D., Farnsworth, N.R., Santisuk, T., Tuchinda, P., Udchachon, J., and Reutrakul, V. Plant antitumor agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots. J. Nat. Prod. 54: 196-206, 1991.

65. Ngassapa, O.D., Soejarto, D.D., Che, C.-T., Pezzuto, J.M., and Farnsworth, N.R. New cytotoxic lupane lactones from Kokoona ochracea. J. Nat. Prod. 54: 1353-1359, 1991.

66. Kardono, L.B.S., Angerhofer, C.K., Tsauri, S., Padmawinata, K., Pezzuto, J.M., and Kinghorn, A.D. Cytotoxic and antimalarial constituents of the roots of Eurycoma longifolia. J. Nat. Prod. 54: 1360-1367, 1991.

67. Pezzuto, J.M., Che, C.-T., McPherson, D.D., Topçu, G., Erdelmeier, C.A.J., and Cordell, G.A. DNA as an affinity probe useful in the detection and isolation of biologically active natural products. J. Nat. Prod. 54: 1522-1530, 1991.

68. Mar, W., Tan, G.T., Cordell, G.A., Pezzuto, J.M., Jurcic, K., Redl, K., Steinke, B., and Wagner, H. Biological activity of novel macrocyclic alkaloids (Budmunchiamines) from Albizia amara detected on the basis of interaction with DNA. J. Nat. Prod., 54: 1531-1542, 1991.

69. Duh, C.-Y., Kinghorn, A.D., and Pezzuto, J.M. Cell cycle specific cytotoxicity mediated by Stizophyllin (2?,3?,12?-trihydroxypregna-4,7,16-trien-20-one), a novel electrophilic pregnane isolated from Stizophyllum riparium. Chem.-Biol. Interactions, 80: 43-56, 1991.

70. Cordell, G.A., Beecher, C.C.W., and Pezzuto, J.M. Can ethnopharmacology contribute to the development of new anticancer drugs? J. Ethnopharmacol. 32: 117-133, 1991.

71. Pezzuto, J.M., Mar, W., Lin, L.-Z., Cordell, G.A., Neszmélyi, A., and Wagner, H. DNA-based isolation and the structure elucidation of the budmunchiamines, novel macrocyclic alkaloids from Albizia amara. Heterocycles 32: 1961-1967, 1991.

72. Fullas, F., Hussain, R.A., Pezzuto, J.M., Soejarto, D.D., Kinghorn, A.D., and Bordas, E. Gaudichaudiosides A-E, five novel diterpene glycoside constituents from the sweet-tasting plant, Baccharis gaudichaudiana. Tetrahedron 47: 8515-8522, 1991.

73. Tan, G.T., Kinghorn, A.D., Hughes, S.H., and Pezzuto, J.M. Psychotrine and its O-methyl ether are selective inhibitors of human immunodeficiency virus-1 reverse transcriptase. J. Biol. Chem. 266: 23529-23536, 1991.

74. Tuchinda, P., Udchachon, J., Reutrakul, V., Santisuk, T., Taylor, W.C., Farnsworth, N.R., Pezzuto, J.M., and Kinghorn, A.D. Bioactive butenolides from Melodorum fruticosum. Phytochemistry 30: 2685-2689, 1991.

75. Dai, J., Kardono, L.B.S., Tsauri, S., Padmanwinata, K., Pezzuto, J.M., and Kinghorn, A.D. Phenylacetic acid derivatives and a thioamide glycoside from Entada phaseoloides. Phytochemistry 30: 3749-3752, 1991.

76. Zong, Y.-Y., Lowell, K., Jiang, P., Che, C.-T., Pezzuto, J.M., and Fong, H.H.S. Phenolic constituents of Rhodiola coccinea, a Tibetan folk medicine. Planta Med. 57: 589, 1991.

77. Kaneda, H., Chai, H., Pezzuto, J.M., Kinghorn, A.D., Farnsworth, N.R., Tuchinda, P., Udchachon, J., Santisuk, T., and Reutrakul, V. Cytotoxic activity of cardenolides from Beaumontia brevituba stems. Planta Med. 58: 429-431, 1992.

78. Pezzuto, J.M., Mar, W., Lin, L.-Z, Cordell, G.A., Neszmélyi, A., and Wagner, H. Budmunchiamines D-I from Albizia amara. Phytochemistry 31: 1795-1800, 1992.

79. Lin, L.-J., Ruangrungsi, N., Cordell, G.A., Shieh, H.-L., You, M., and Pezzuto, J.M. 6-Deoxyclitoriacetal from Clitoria macrophylla. Phytochemistry 31: 4329-4331, 1992.

80. Lin, L.-J., Topçu, G., Lotter, H., Ruangrungsi, N., Wagner, H., Pezzuto, J.M., and Cordell, G.A. Wrightiadione from Wrightia tomentosa. Phytochemistry 31: 4333-4335, 1992.

81. Shieh, H.-L., Pezzuto, J.M., and Cordell, G.A. Evaluation of the cytotoxic mechanism mediated by the broad-spectrum antitumor compound acronycine and semisynthetic derivatives. Chem.-Biol. Interactions 81: 35-55, 1992.

82. Kaneda, N., Pezzuto, J.M., Kinghorn, A.D., Farnsworth, A.D., Santisuk, T., Tuchinda, P., Udchachon, J., and Reutrakul, V. Plant anticancer agents, L. Cytotoxic triterpenes from Sandoricum koetjape Stems. J. Nat. Prod. 55: 654-659, 1992.

83. Angerhofer, C.K., Pezzuto, J.M., König, G.M., Wright, A.D., and Sticher, O. Antimalarial sesquiterpenes from the marine sponge, Acanthella klethra. J. Nat. Prod. 55: 1787-1789, 1992.

84. Tan, G.T., Miller, J., Kinghorn, A.D., Hughes, S.H., and Pezzuto, J.M. HIV-1 and HIV-2 reverse transcriptases: a comparative study of sensitivity to inhibition by selected natural products. Biochem. Biophys. Res. Commun. 185: 370-378, 1992.

85. Gerhäuser, C., Leonhardt, K., Tan, G.T., Pezzuto, J.M., and Wagner, H. What is the active antiviral principle of Thuja occidentalis L.? Pharm. Pharmacol. Lett. 2: 127-130, 1992.

86. Tan, G.T., Wickramasinghe, A., Verma, S., Singh, R., Hughes, S.H., Pezzuto, J.M., Baba, M., and Mohan, P. Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1-induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities. J. Med. Chem. 35: 4846-4853, 1992.

87. Lin, L.-Z., Shieh, H.-L., Angerhofer, C.K., Pezzuto, J.M., Cordell, G.A., Xue, L., Johnson, M.E., and Ruangrungsi, N. Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Cyclea barbata. J. Nat. Prod. 56: 22-29, 1993.

88. Likhitwitayawuid, K., Angerhofer, C.K., Cordell, G.A., Pezzuto, J.M., and Ruangrungsi, N. Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Stephania erecta. J. Nat. Prod. 56: 30-38, 1993.

89. Somanabandhu, A., Nitayangkura, S., Mahidol, C., Ruchirawat, Likhitwitayawuid, K.-S., Shieh, H.-L., Chai, H., Pezzuto, J.M., and Cordell, G.A. 1H- and 13C-NMR assignments of phyllanthin and hypophyllanthin: lignans that enhance cytotoxic responses with multidrug- resistant cells. J. Nat. Prod. 56: 233-239, 1993.

90. Saifah, E., Likhitwitayawuid, K., Puripattanavong, J., Cordell, G.A., Chai, J., and Pezzuto, J.M. Bisamides from Aglaia Species: structure analysis and potential to reverse drug resistance with cultured cells. J. Nat. Prod. 56: 473-477, 1993.

91. Pereda-Miranda, R., Mata, R., Anaya, A.L., Pezzuto, J.M., Chai, H., Dias, M., Wickramaratne, M., and Kinghorn, A.D. Tricolorin A, major phytogrowth-inhibitor from Ipomoea tricolor. J. Nat. Prod. 56: 571-582, 1993.

92. Pereda-Miranda, R., Hernández, L., Villavicencio, M.J., Novelo, M., Ibarra, P., Chai, H., and Pezzuto, J.M. Structure and stereochemistry of Pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-?-pyrones from Hyptis pectinata. J. Nat. Prod. 56: 583-593, 1993.

93. Likhitwitayawuid, K., Angerhofer, C.K., Chai, H., Pezzuto, J.M., Cordell, G.A., and Ruangrungsi, N. Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile. J. Nat. Prod. 56: 1331-1338, 1993.

94. Antoun, M.D., Ríos, Y.R., Mendoza, N.T., Wickramaratne, D.B.N., Pezzuto, J.M., and Kinghorn, A.D. Cytotoxicity of Hymenocallis expansa alkaloids. J. Nat. Prod. 56: 1423-1425, 1993.

95. Likhitwitayawuid, K., Angerhofer, C.K., Chai, H., Pezzuto, J.M., Cordell, G.A., and Ruangrungsi, N. Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei. J. Nat. Prod. 56: 1468-1478, 1993.

96. Baek, N.-I., Chung, M.-S., Shamon, L., Kardono, L.B.S., Tsauri, S., Padmawinata, K., Pezzuto, J.M., Soejarto, D.D., and Kinghorn, A.D. Selligueain A, a novel highly sweet proanthocyanidin from the rhizomes of Selliguea feii. J. Nat. Prod. 56: 1532-1538, 1993.

97. Ngassapa, O.D., Soejarto, D.D., Pezzuto, J.M., Farnsworth, N.R., and Che, C.-T. Further lupane lactones from Kokoona ochracea. J. Nat. Prod. 56: 1676-1681, 1993.

98. Novelo, M., Cruz, J.G., Hernández, L., Perdea-Miranda, R., Chai, H., Mar, W., and Pezzuto, J.M. Cytotoxic constituents from Hyptis verticillata. J. Nat. Prod. 56: 1728-1736, 1993.

99. Nsassapa, O., Beecher, C.W.W., Pezzuto, J.M., Farnsworth, N.R., Henderson, T.O., and Boye, G.L. Isolation of echinocystic acid 3-O-sulfate, a new triterpene from Tetrapleura tetraptera, and evaluation of the mutagenic potential of molluscicidal extracts and isolates. J. Nat. Prod. 56: 1872-1877, 1993.

100. Luyengi, L., Pezzuto, J.M., Waller, D.P., Beecher, C.W.W., Fong, H.H.S., Che, C.-T., and Bowen, P.E. Linusitamarin, a new phenylpropanoid glucoside from Linum usitatissimum. J. Nat. Prod. 56: 2012-2015, 1993.

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