Dean, College of Pharmacy
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401. Hwang, B.Y., Su, B.N., Chai, H., Mi, Q., Kardono, L.B., Afriastini, J.J., Riswan, S., Santarsiero, B.D., Mesecar, A.D., Wild, R., Fairchild, C.R., Vite, G.D., Rose, W.C., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., and Kinghorn, A.D. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. J. Org. Chem., 69: 6156, 2004.
402. Jang, D.S., Cuendet, M., Su, B.-N., Totura, S., Riswan, S., Fong, H.H.S., Pezzuto, J.M., and Kinghorn, A.D. Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2. Planta Med., 70: 893-896, 2004.
403. Gafner, S., Lee, S.K., Cuendet, M., Barthelemy, S., Vergnes, L., Labidalle, S., Mehta, R.G., Boone, C.W., and Pezzuto, J.M. Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems. Phytochemistry, 65: 2849-2859, 2004.
404. Su, B.N., Jones, W.P., Cuendet, M., Kardono, L.B., Ismail, R., Riswan, S., Fong, H.H., Farnsworth, N.R., Pezzuto, J.M., and Kinghorn, A.D. Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2. Phytochemistry, 65: 2861-2866, 2004.
405. Kondratyuk, T. and Pezzuto, J.M. Natural product polyphenols of relevance to human health. Pharm. Biol. (Suppl.), 41: 46-63, 2004.
406. Tamez, P.A., Lantvit, D., Lim, E., and Pezzuto, J.M. Chemosensitizing action of cepharanthine with chloroquine against drug-resistant human malaria, Plasmodium falciparum. J. Ethnopharmacol., 98: 137-142, 2005.
407. Lobo-Echeverri, T., Rivero-Cruz, J.F., Su, B.-N., Chai, H.-B., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., Soejarto, D.D., and Kinghorn, A.D.. Constituents of the leaves and twigs of Calyptranthes pallens collected from an experimental plot in southern Florida. J. Nat. Prod., 68: 577-580, 2005.
408. Rivero-Cruz, J.F., Lezutekong, R., Lobo-Echeverri, T., Ito, A., Mi, Q., Chai, H.-B., Soejarto, D.D., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., Morelli, I., and Kinghorn, A.D. Cytotoxic constituents of the twigs of Simarouba glauca collected from a plot in southern Florida. Phytother. Res., 19: 136-140, 2005.
409. Mi, Q., Lantvit, D., Reyes-Lim, E., Chai, H., Phifer, S.S., Wani, M.C., Wall, M.E. Tan, G.T., Cordell, G.A., Farnsworth, N.R., Kinghorn, A.D. and Pezzuto, J.M. Apoptotic anticancer effect of alvaradoin E isolated from Alvaradoa haitiensis. Anticancer Res., 25: 779-788, 2005.
410. Zhang. H.J., Hung, N.V., Cuong, N.M., Soejarto, D.D., Pezzuto, J.M., Fong, H.H., and Tan, G.T. Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata. Planta Med., 71: 452-457, 2005.
411. Chow, A.W., Murillo, G., Yu, C., van Breemen, R.B., Boddie, A.W., Pezzuto, J.M., Das Gupta, T.K., and Mehta, R.G. Resveratrol inhibits rhabdomyosarcoma cell proliferation. Eur. J. Cancer Prev., 14: 351-356, 2005.
412. Eggler, A.L., Liu, G., Pezzuto, J.M., van Breemen, R.B., and Mesecar, A.D. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc. Natl. Acad. Sci. U S A, 102: 10070-10075, 2005.
413. Jang, D.S., Su, B.-N., Pawlus, A.D., Jones, W.P., Kleps, R.A., Bunyapraphatsara, N., Fong, H.H.S., Pezzuto, J.M., and Kinghorn, A.D. Limnophilaspiroketone, a highly oxygenated phenolic derivative from Limnophila geoffrayi. J. Nat. Prod., 68: 1134-1136, 2005.
414. Gills, J.J., Kosmeder III, J., Moon, R.C., Lantvit, D.D., and Pezzuto, J.M. Effect of deguelin on UVB-induced skin carcinogenesis. J. Chemother., 3: 297-301, 2005.
415. Jones, W.P., Lobo-Echiverri, T., Mi, Q., Chai, H., Lee, D., Soejarto, D.D., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., and Kinghorn, A.D. Antitumor activity of 3-chlorodeoxylapachol, a naphthoquinone from Avicennia germinans collected from an experimental plot in southern Florida. J. Pharm. Pharmacol., 57: 1101-1108.
416. Soejarto, D.D., Fong, H.H.S., Tan, G.T., Zhang, H.J., Ma, C.Y., Franzblau, S.G., Gyllenhaal, C., Riley, M.C., Kadushin, M.R., Pezzuto, J.M., Xuan, L.T., Hiep, N.T., Hung, N.V., Vu, B.M., Loc, P.K., Dac, L.X., Binh, L.T., Chien, N.Q., Hai, N.V., Bich, T.Q., Cuong, N.M., Southavong, B., Sydara, K., Bouamanivong, S., Ly, H.M., Tran Van Thuy, Rose, W.C., and Dietzman, G.R. Ethnobotany/Ethnopharmacology and mass bioprospecting: Issues on intellectual property and benefit-sharing. J. Ethnopharmacol., 100: 15-22, 2005.
417. Liu, G., Eggler, A.L., Dietz, B.M., Mesecar, A.D., Bolton, J.L., Pezzuto, J.M., and van Breemen, R.B. Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1. Anal. Chem., 77: 6407-6414, 2005.
418. Lee, H.-Y., Oh, S.-H., Jin, Q., Woo, J.K., Kim, W.-Y., Van Pelt, C.S., Price, R.E., Cody, D., Tran, H., Pezzuto, J.M., Moriarty, R.M., and Hong, W.K. Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. J. Natl. Cancer Inst., 97: 1695-1699, 2005.
419. He, Z.D., Ma, C.Y., Zhang, H.J., Tan, G.T., Tamez, P., Sydara, K., Bouamanivong, S., Southavong, B., Soejarto, D.D., Pezzuto, J.M., and Fong, H.H. Antimalarial constituents from Nauclea orientalis (L.) L. Chem. Biodivers., 2: 1378-1386, 2005.
420. Zhang, H.-J., Ma, C., Hung, NV, Cuong, NM, Tan, G.T., Santarsiero, B.D., Mesecar, A.D., Soejarto, D.D., Pezzuto, J.M., and Fong, H.H.S. Miliusanes, a class of cytotoxic agents from Miliusa sinensis. J. Med. Chem., 49: 693-708, 2006.
421. Homhual, S., Zhang, H.-J., Bunyapraphatsara, N., Kondratyuk, T.P., Santarsiero, B.D., Mesecar, A.D., Herunsalee, A., Chaukul, W., Pezzuto, J.M., and Fong, H.H.S. Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza. Planta Med., 72: 255-260, 2006.
422. Homhual, S., Bunyapraphatsara, N., Kondratyuk, T.P., Herunsalee, A., Chaukul, W., Pezzuto, J.M., Fong, H.H.S., and Zhang, H.-J. Bioactive dammarane triterpenes from the mangrove plant Bruguiera gymnorrhiza. J. Nat. Prod., 69: 421-424, 2006.
423. Soejarto, D.D., Zhang, H.J., Fong, H.H.S., Tan, G.T., Ma, C.Y., Gyllenhaal, C., Riley, M.C., Kadushin, M.R., Franzblau, S.G., Bich, T.Q., Cuong, N.M., Hiep, N.T., Loc, P.K., Xuan, L.T., Hai, N.V., Hung, N.V., Chien, N.Q., Binh, L.T., Vu, B.M., Ly, H.M., Southavong, B., Sydara, K., Bouamanivong, S., Pezzuto, J.M., Rose, W., Dietzman, G., Miller, B., and Thuy, T.V. Studies on biodiversity of Vietnam and Laos, 1998-2005: Examining the impacts. J. Nat. Prod., 69: 473-481, 2006.
424. Cuendet, M., Oteham, C.P., Moon, R.C., and Pezzuto, J.M. Quinone reductase induction as a biomarker for cancer chemoprevention. J. Nat. Prod., 69: 460-463, 2006.
425. Fang, L., Ito, A., Chai, H.-B., Mi, Q., Jones, W.P., Madulid, D.R., Oliveros, M.B., Gao, Q., Orjala, J., Farnsworth, N.R., Soejarto, D.D., Cordell, G.A., Swanson, S.M., Pezzuto, J.M., and Kinghorn, A.D. Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines. J. Nat. Prod., 69: 332-337, 2006.
426. Carcache-Blanco, E.J., Cuendet, M., Park, E.J., Su, B.-N., Rivero-Cruz, J.F., Farnsworth, N.R. Pezzuto, J.M., and Kinghorn, A.D. Potential cancer chemopreventive agents from Arbutus unedo. Nat. Prod. Res., 20: 327-334, 2006.
427. Gills, J.J., Jeffery, E.H., Matusheski, N.V., Moon, R.C., Lantvit, D.D., and Pezzuto, J.M. Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion. Cancer Lett., 236: 72-79, 2006.
428. Wright, A.D., de Nys, R., Angerhofer, C.K., Pezzuto, J.M., and Gurrath, M. Biological activities and 3D QSAR studies of a series of Delisea pulchra (cf. fimbriata) derived natural products. J. Nat. Prod., 69:1180-1187, 2006.
429. Jang, D.S., Su, B.N., Pawlus, A.D., Kang, Y.H., Kardono, L.B., Riswan, S., Afriastini, J.J., Fong, H.H., Pezzuto, J.M., and Kinghorn, A.D. Beccaridiol, an unusual 28-nortriterpenoid from the leaves of Diplectria beccariana. Phytochemistry, 67: 1832-1837, 2006.
430. He, Z.D., Ma, C.Y., Tan, G.T., Sydara, K., Tamez, P., Southavong, B., Bouamanivong, S., Soejarto, D.D., Pezzuto, J.M., Fong, H.H., and Zhang, H.J. Rourinoside and rouremin, antimalarial constituents from Rourea minor. Phytochemistry, 67:1378-1384, 2006.
431. Choi, J.K., Murillo, G., Su, B.N., Pezzuto, J.M., Kinghorn, A.D., and Mehta, R.G. Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells. FEBS J., 273: 5714-5723, 2006.
432. Thole, J.M., Kraft, T.F., Sueiro, L.A., Kang, Y.H., Gills, J.J., Cuendet, M., Pezzuto, J.M., Seigler, D.S., and Lila, M.A. A comparative evaluation of the anticancer properties of European and American elderberry fruits. J. Med. Food, 9: 498-504, 2006.
433. Balunas, M.J., Jones, W.P., Chin, Y.W., Mi, Q., Farnsworth, N.R., Soejarto, D.D., Cordell, G.A., Swanson, S.M., Pezzuto, J.M., Chai, H.B., and Kinghorn, A.D. Relationships between inhibitory activity against a cancer cell line panel, profiles of plants collected, and compound classes isolated in an anticancer drug discovery project. Chem Biodivers., 3: 897-915, 2006.
434. Cuendet, M., Mesecar, A.D., Dewitt, D.L. and Pezzuto, J.M. Cyclooxygenase (Cox 1 & 2) activity assays. Nature Protocols . 1: 1922-1928, 2006.
435. Williams, P.G., Asolkar, R.N., Kondratyuk, T., Pezzuto, J.M., Jensen, P.R., and Fenical, W. Saliniketals A and B, bicyclic polyketides from the marine actinomycete Salinispora arenicola. J. Nat. Prod., 70: 83-88, 2007.
436. Maiti, A., Cuendet, M., Kondratyuk, T., Croy, V.L., Pezzuto, J.M., and Cushman, M. Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. J. Med. Chem., 50: 350-355, 2007.
437. Murillo, G., Hirschelman, W.H., Ito, A., Moriarty, R.M., Kinghorn, A.D., Pezzuto, J.M., and Mehta, R.G. Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis. Nutr. Cancer, 57: 28-37, 2007.
438. Maiti, A., Cuendet, M., Croy, V.L., Endringer, D.C., Pezzuto, J.M., and Cushman, M. Synthesis and biological evaluation of (±)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer. J. Med. Chem., 50: 2799-2806, 2007.
439. Jutiviboonsuk, A., Zhang, H.-J., Kondratyuk, T.P., Herunsalee, A., Chaukul, W., Pezzuto, J.M., Fong, H.H.S., and Bunyapraphatsara, N. Isolation and characterization of cancer chemopreventive compounds from Barringtonia maunwongyathiae. Pharm. Biol., 45: 185-194, 2007.
440. Liu D, Guo J, Luo Y, Broderick DJ, Schimerlik MI, Pezzuto JM, Breemen RB. Screening for ligands of human retinoid X receptor-alpha using ultrafiltration mass spectrometry. Anal. Chem., 79: 9398-9402, 2007.
441. Guo J, Liu D, Nikolic D, Zhu D, Pezzuto JM, van Breemen RB. In vitro metabolism of isoliquiritigenin by human liver microsomes. Drug Metab. Dispos., 36: 461-468, 2008.
442. Book Chapters
443. Yang, C.S. and Pezzuto, J.M. Nuclear Aryl Hydrocarbon Hydroxylase and Its Role in the Activation of Benzo(a)pyrene. In: P.W. Jones and P. Leber (eds.), Polynuclear Aromatic Hydrocarbons, pp. 653-667. Ann Arbor Science Publishers, 1979.
444. Pezzuto, J.M. and Phoebe, Jr., C.H. "Laboratory Text in Pharmacognosy 233." Published by the Authors, 37 pp., 1982.
445. Farnsworth, N.R. and Pezzuto, J.M. Practical Pharmacologic Evaluation of Plants. In: Pharmacological Screening of Plants and Natural Substances. No. 13, pp. 138-160. International Foundation for Science, Stockholm, 1983.
446. Farnsworth, N.R. and Pezzuto, J.M. Rational Approaches to the Development of Plant-Derived Drugs. In: Proceedings of the Second National Symposium of Natural Products Pharmacology and Chemistry, Nov. 3-5, 1983, Joao Pessoa, Brazil, pp. 35-63. University Editors, Federal University of Paraiba, 1984.
447. Farnsworth, N.R. and Pezzuto, J.M. Practical Pharmacologic Evaluation of Plants. In: B. Conyers (ed.), Bulletin 21 of the Air Chief Marshal the Lord Dowding Fund for Humane Research, pp. 26-34. National Anti-Vivisection Society Limited, London, 1984 (reprinted from a paper presented at the University of Panama).
448. Pezzuto, J.M. Chemistry, Metabolism and Biological Activity of Steviol (ent-13-Hydroxykaur-16-en-19-oic Acid), the Aglycone of Steviol. In: Atta-ur-Rahman and P.W. LeQuesne (eds.), New Trends in Natural Products Chemistry. 1986. Studies in Organic Chemistry, Vol. 26, pp. 371-386. Elsevier Scientific Publishers, 1986.
449. Swanson, S.M. and Pezzuto, J.M. Bioscreening for Antitumor Activity: Evaluation of Cytotoxic Potential and Ability to Inhibit Macromolecule Biosynthesis. In: E.B. Thompson (ed.), Drug Bioscreening. Drug Evaluation Techniques in Pharmacology, pp. 273-297. New York: VCH Publishers, 1990.
450. Suffness, M. and Pezzuto, J.M. Assays for Cytotoxicity and Antitumor Activity, Chapter 4. In: K. Hostettmann (ed.), Methods in Plant Biochemistry, Vol. 6, pp. 71-133. London: Academic Press, 1991.