Dean, College of Pharmacy
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351. Chun, K.H., Kosmeder, J.W. 2nd, Sun, S., Pezzuto, J.M., Lotan, R., Hong, W.K., and Lee, H.Y. Effects of deguelin on the phosphatidylinositol 3-kinase/akt pathway and apoptosis in premalignant human bronchial epithelial cells. J. Natl. Cancer Inst., 95: 291-302, 2003.
352. Su, B.N., Park, E.J., Nikolic, D., Santarsiero, B.D., Mesecar, A.D., Vigo, J.S., Graham, J.G., Cabieses, F., van Breemen, R.B., Fong, H.H., Farnsworth, N.R., Pezzuto, J.M., Kinghorn, A.D. Activity-guided isolation of novel norwithanolides from Deprea subtriflora with potential cancer chemopreventive activity. J. Org. Chem., 68: 2350-2361, 2003.
353. Zhang, H.-J., Tan, G.T., Hoang, V.D., Hung, N.V., Cuong, N.M., Soejarto, D.D., Pezzuto, J.M., and Fong, H.H.S. Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea. J. Nat. Prod., 66: 263-268, 2003.
354. Seo, E.-K., Lee, D., Shin, Y.G., Chai, H.-B., Navarro, H.A., Kardono, L.B., Rahman, I., Cordell, G.A., Farnsworth, N.R., Pezzuto, J.M., Kinghorn, A.D., Wani, M.C., and Wall, M.E. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Arch. Pharm. Res., 26: 124-127, 2003.
355. Su, B.-N., Cuendet, M., Nikolic, D., Kristinsson, H., Ingólfsdóttir, van Breemen, R.B., Fong, H.H.S., Pezzuto, J.M., and Kinghorn, A.D. NMR study of fumarprotocetraric acid, a complex lichen depsidone derivative from Cladonia furcata. Magn. Resonance Chem., 41: 391-394, 2003.
356. Gafner, S., Bergeron, C., Batcha, L.L., Reich, J., Arnason, J.T., Burdette, J.E., Pezzuto, J.M., and Angerhofer, C.K. Inhibition of [(3)H]-LSD binding to 5-HT(7) receptors by flavonoids from Scutellaria lateriflora. J. Nat. Prod., 66: 535-537, 2003.
357. Gu, J.-Q., Li, W., Kang, Y.-H., Su, B.-N., Fong, H.H.S., van Breemen, R.B., Pezzuto, J.M., and Kinghorn, A.D. Minor withanolides from Physalis philadelphica: Structures, quinone reductase induction activities, and LC-MS-MS investigation as artifacts. Chem. Pharm. Bull. (Tokyo), 51: 530-539, 2003.
358. Su, B.-N., Park, E.J., Vigo, J.S., Graham, J.G., Cabieses, F., Fong, H.H.S., Pezzuto, J.M., and Kinghorn, A.D. Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay. Phytochemistry, 63: 335-341, 2003.
359. Fang, L., Chai, H.-B., Castillo, J.J., Soejarto, D.D., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., and Kinghorn, A.D. Cytotoxic constituents of Brachistus stramoniifolius. Phytochem. Res., 17: 520-523, 2003.
360. Jang, D.S., Park, E.J., Hawthorne, M.E., Vigo, J.S., Graham, J.G., Cabieses, F., Santarsiero, B.D., Mesecar, A.D., Fong H.H.S., Mehta, R.G., Pezzuto, J.M., and Kinghorn, A.D. Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (Tonka Bean). J. Nat. Prod., 66: 583-587, 2003.
361. Zhang, H.-J., Tan, G.T., Santarsiero, B.D., Mesecar, A.D., Hung, N.V., Cuong, N.M., Soejarto, D.D., Pezzuto, J.M., and Fong, H.H.S. New sesquiterpenes from Litsea verticillata. J. Nat. Prod., 66: 609-615, 2003.
362. Topcu, G., Altiner, E.N., Gozcu, S., Halfon, B., Aydogmus, Z., Pezzuto, J.M., Zhou, B.N., and Kingston, D.G. Studies on di- and triterpenoids from Salvia staminea with cytotoxic activity. Planta Med., 69: 464-467, 2003.
363. Omar, S., Zhang, J., MacKinnon, S., Leaman, D., Durst, T., Philogene, B.J.R., Arnason, J.T., Sanchez-Vindas, P.E., Poveda, L., Tamez, P.A., and Pezzuto, J.M. Traditionally-used antimalarials from the Meliaceae. Curr. Topics in Med. Chem., 3: 21-27, 2003.
364. Diaz, F., Chavez, D., Lee, D., Mi, Q., Chai, H.B., Tan, G.T., Kardono, L.B., Riswan, S., Fairchild, C.R., Wild, R., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., and Kinghorn, A.D. Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. J. Nat. Prod. 66: 865-867, 2003.
365. Tan, Y., Yu, R., and Pezzuto, J.M. Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase activation. Clin. Cancer Res., 9: 2866-2875, 2003.
366. Su, B.N., Park, E.J., Nikolic, D., Vigo, J.S., Graham, J.G., Cabieses, F., van Breemen, R.B., Fong, H.H.S., Farnsworth, N.R., Pezzuto, J.M., and Kinghorn, A.D. Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. J. Nat. Prod., 66: 1089-1093, 2003.
367. Su, B.N., Kang, Y.H., Pinos, R.E., Santarsiero, B.D., Mesecar, A.D., Soejarto, D.D., Fong, H.H., Pezzuto, J.M., and Kinghorn A.D. Isolation and absolute stereochemistry of coussaric acid, a new bioactive triterpenoid from the stems of Coussarea brevicaulis. Phytochemistry, 64: 293-302, 2003.
368. Burdette, J.E., Liu, J., Chen, S.N., Fabricant, D.S., Piersen, C.E., Barker, E.L., Pezzuto, J.M., Mesecar, A., van Breemen, R.B., Farnsworth, N.R., and Bolton, J.L. Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. J. Agric. Food Chem., 51: 5661-5670, 2003.
369. Jang, D.S., Park, E.J., Kang, Y.H., Su, B.N., Hawthorne, M.E., Vigo, J.S., Graham, J.G., Cabieses, F., Fong, H.H., Mehta, R.G., Pezzuto, J.M., and Kinghorn, A.D. Compounds obtained from Sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model. Arch. Pharm. Res., 26: 585-590, 2003.
370. Carcache-Blanco, E.J., Kang, Y.H., Park, E.J., Su, B.N., Kardono, L.B., Riswan, S., Fong, H.H., Pezzuto, J.M., and Kinghorn, A.D. Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase. J. Nat. Prod., 66: 1197-1202, 2003.
371. Jang, D.S., Park, E.J., Kang, Y.H., Hawthorne, M.E., Vigo, J.S., Graham, J.G., Cabieses, F., Fong, H.H.S., Mehta, R.G., Pezzuto, J.M., and Kinghorn, A.D. Potential cancer chemopreventive flavonoids from the stems of Tephrosia toxicaria. J. Nat. Prod., 66: 1166-1170, 2003.
372. Burdette, J.E., Liu, J., Chen, S., Fabricant, D.S., Piersen, C.E., Barker, E.L., Pezzuto, J.M., Mesecar, A., van Breemen, R.B., Farnsworth, N.R., and Bolton, J.L. Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. J. Agric. Food Chem., 51: 5661-5670, 2003.
373. Lee, K.H., Chai, H.B., Tamez, P.A., Pezzuto, J.M., Cordell, G.A., Win, K.K., and Tin-Wa M. Biologically active alkylated coumarins from Kayea assamica. Phytochemistry, 64: 535-541, 2003.
374. Topcu, G., Aydogmus, Z., Imre, S., Goren, A.C., Pezzuto, J.M., Clement, J.A., and Kingston, D.G. Brominated sesquiterpenes from the red alga Laurencia obtusa. J. Nat. Prod., 66: 1505-1508, 2003.
375. Mi, Q., Cui, B., Lantvit, D., Reyes-Lim, E., Chai, H., Pezzuto, J.M., Kinghorn, A.D., and Swanson, S.M. Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance. Anticancer Res., 23: 3607-3615, 2003.
376. Li, Y., Shin, Y.G., Yu, C., Kosmeder, J.W., Hirschelman, W.H., Pezzuto, J.M., and van Breemen, R.B. Increasing the throughput and productivity of caco-2 cell permeability assays using liquid chromatography-mass spectrometry: application to resveratrol absorption and metabolism. Comb. Chem. High Throughput Screen., 6: 757-767, 2003.
377. Kinghorn, A.D., Farnsworth, N.R., Soejarto, D.D., Cordell, G.A., Swanson, S.M., Pezzuto, J.M., Wani, M.C., Wall, M.E., Oberlies, N.H., Kroll, D.J., Kramer, R.A., Rose, W.C., Vite, G.D., Fairchild, C.R., Peterson, R.W., and Wild, R. Novel strategies for the discovery of plant-derived anticancer agents. Pharm. Biol., 41 (Suppl.): 53-67, 2003.
378. Villinski, J.R., Dumas, E.R., Chai, H.-B., Pezzuto, J.M., Angerhofer, C.K., and Gafner, S. Antimicrobial activity and alkaloid content of Berberis thunbergii, Berberis vulgaris and Hydrastis canadensis. Pharm. Biol., 41: 551-557, 2003.
379. Carcache-Blanco, E.J., Kang, Y.H., Park, E.J., Su, B.N., Kardono, L.B., Riswan, S., Fong, H.H., Pezzuto, J.M., and Kinghorn, A.D. Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase. J. Nat. Prod., 67: 126, 2004.
380. Jang, D.S., Cuendet, M., Pawlus, A.D., Kardono, L.B., Kawanishi, K., Farnsworth, N.R., Fong, H.H., Pezzuto, J.M., and Kinghorn, A.D. Potential cancer chemopreventive constituents of the leaves of Macaranga triloba. Phytochemistry. 65: 345-350, 2004.
381. Liu, J., Burdette, J.E., Sun, Y., Deng, S., Schlecht, S.M., Zheng, W., Nikolic, D., Mahady, G., van Breemen, R.B., Fong, H.H., Pezzuto, J.M., Bolton, J.L., and Farnsworth, N.R. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry). Phytomedicine. 11: 18-23, 2004.
382. Cuendet, M., Christov, K., Lantvit, D.D., Deng, Y., Hedayat, S., Helson, L., McChesney, J.D., and Pezzuto, J.M. Multiple myeloma regression mediated by bruceantin. Clin. Cancer Res., 10: 1170-1179, 2004.
383. Lee, H.Y., Suh, Y.A., Kosmeder, J.W., Pezzuto, J.M., Hong, W.K., and Kurie, J.M. Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells. Clin. Cancer Res., 10: 1074-1079, 2004.
384. Soejarto, D.D., Gyllenhaal, C., Fong, H.H., Xuan, L.T., Hiep, N.T., Hung, N.V., Bich, T.Q., Southavong, B., Sydara, K., and Pezzuto, J.M. The UIC ICBG (University of Illinois at Chicago International Cooperative Biodiversity Group) Memorandum of Agreement: A model of benefit-sharing arrangement in natural products drug discovery and development. J. Nat. Prod., 67: 294-299, 2004.
385. Cuendet, M. and Pezzuto, J.M. Antitumor activity of bruceantin: An old drug with new promise. J. Nat. Prod., 67: 269-272, 2004.
386. Ito, A., Chai, H.B., Kardono, L.B., Setowati, F.M., Afriastini, J.J., Riswan, S., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., and Kinghorn, A.D. Saponins from the bark of Nephelium maingayi. J. Nat. Prod., 67: 201-205, 2004.
387. Zhang, H.J., Sydara, K., Tan, G.T., Ma, C., Southavong, B., Soejarto, D.D., Pezzuto, J.M., and Fong, H.H. Bioactive constituents from Asparagus cochinchinensis. J. Nat. Prod., 67: 194-200, 2004.
388. Su, B.-N., Gu, J.-Q., Kang, Y.-H., Park, E.J., Pezzuto, J.M., and Kinghorn, A.D. Induction of the phase II enzyme, quinone reductase, by withanolides and norwithanolides from Solanaceous species. Mini-Rev. Org. Chem., 1: 115-123, 2004.
389. Cuendet, M., Gills, J.J., and Pezzuto, J.M. Brusatol-induced HL-60 cell differentiation involves NF-?B activation. Cancer Lett., 206: 43-50, 2004.
390. Jang, D.S., Park, E.J., Kang, Y.H., Vigo, J.S., Graham, J.G., Cabieses, F., Fong, H.H., Pezzuto, J.M., and Kinghorn, A.D. Phenolic compounds obtained from stems of Couepia ulei with the potential to induce quinone reductase. Arch. Pharm. Res., 27: 169-172, 2004.
391. Diaz, F., Chai, H.B., Mi, Q., Su, B.N,, Vigo, J.S., Graham, J.G., Cabieses, F., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., and Kinghorn, A.D. Anthrone and oxanthrone C-glycosides from Picramnia latifolia collected in Peru. J. Nat. Prod., 67: 352-356, 2004.
392. Rivero-Cruz, J.F., Chai, H.B., Kardono, L.B., Setyowati, F.M., Afriatini, J.J., Riswan, S., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., and Kinghorn, A.D. Cytotoxic constituents of the twigs and leaves of Aglaia rubiginosa. J. Nat. Prod., 67: 343-347, 2004.
393. Jang, D.S., Cuendet, M., Fong, H.H., Pezzuto, J.M., and Kinghorn, A.D. Constituents of Asparagus officinalis evaluated for inhibitory activity against cyclooxygenase-2. J. Agric. Food Chem., 52: 2218-2222, 2004.
394. Shin, Y.G., Udeani, G.O., Kosmeder II, J.W., Zhao, G.-M., Dagar, S., Onyuksel, H., Moriarty, R.M. Cordell, G.A., Moon, R.C., Kinghorn, A.D., and Pezzuto, J.M. Identification of degradation product of deguelin and its stability using liquid chromatography and electrospray/mass spectrometry. J. Liquid Chrom. Rel. Technol., 27: 1057-1069, 2004.
395. Hwang, B.Y., Su, B.-N., Chai, H., Mi, Q., Kardono, L.B.S., Afriastini, J.J., Riswan, S., Santarsiero, B.D., Mesecar, A.D., Wild, R., Fairchild, C.R., Vite, G.D., Rose, W.C., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., and Kinghorn, A.D. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. J. Org. Chem., 69: 3350-3358, 2004.
396. Christov, K.T., Moon, R.C., Lantvit, D.D., Boone, C.W., Kelloff, G.J., Steele, V.E., Lubet, R.A., and Pezzuto, J.M. Prostate intraepithelial neoplasia in Noble rats, a potential intermediate endpoint for chemoprevention studies. Eur. J. Cancer, 40: 1404-1411, 2004.
397. Chien, N.Q., Hung, N.V., Santarsiero, B.D., Mesecar, A.D., Cuong, N.M., Soejarto, D.D., Pezzuto, J.M., Fong, H.H., and Tan, G.T. New 3-O-acyl betulinic acids from Strychnos vanprukii Craib. J. Nat. Prod., 67: 994-998, 2004.
398. Li, Y., Grubjesic, S., Nikolic, D., Zhu, D., Kosmeder, J.W., Moriarty, R.M., Pezzuto, J.M., and van Breemen, R.B. In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent. Xenobiotica, 34: 535-547, 2004.
399. Gu, J.Q., Graf, T.N., Lee, D., Chai, H.B., Mi, Q., Kardono, L.B., Setyowati, F.M., Ismail, R., Riswan, S., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., Swanson, S.M., Kroll, D.J., Falkinham, J.O. 3rd, Wall, M.E., Wani, M.C., Kinghorn, A.D., and Oberlies, N.H. Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia. J Nat Prod., 67: 1156-1161, 2004.
400. Kinghorn, A.D., Su, B.-N., Jang, D.S., Chang, L.C., Lee, D., Gu, J., Carcache-Blanco, E.J., Pawlus, A.D., Lee, S.K., Park, E.J., Cuendet, M., Gills, J.J., Bhat, K., Park, H.S., Mata-Greenwood, E., Song, L.L., Jang, M., and Pezzuto, J.M. Natural inhibitors of carcinogenesis. Planta Med., 70: 691-705, 2004.