Dean, College of Pharmacy
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301. Hoang, V.D., Tan, G.T., Zhang, H.-J., Tamez, P.A., Hung, N.V., Cuong, N.M., Soejarto, D.D., Fong, H.H.S., and Pezzuto, J.M. Natural anti-HIV agents. Part I. (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata. Phytochemistry, 59: 325-329, 2002.
302. Dharmaratne, H.R.W., Tan, G.T., Marasinghe, G.P.K., and Pezzuto, J.M. Inhibition of HIV-1 reverse transcriptase and HIV-1 replication by Calophyllum coumarins and xanthones. Planta Med., 68: 86-87, 2002.
303. Kandil, F.E., Smith, M.A., Rogers, R.B., Pepin, M.F., Song, L.L., Pezzuto, J.M., and Seigler, D.S. Composition of a chemopreventive proanthocyanidin-rich fraction from cranberry fruits responsible for the inhibition of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced ornithine decarboxylase (ODC) activity. J. Agric. Food Chem., 50: 1063-1069, 2002.
304. Perzaz-Sánchez, S.R., Chai, H.-B., Shin, Y.G., Santisuk, T., Reutrakul, V., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., and Kinghorn, A.D. Constituents of the leaves and twigs of Ficus hispida. Planta Med., 68: 186-188, 2002.
305. Zhang, H., Fan, Z., Tan, G.T., Chai, H.B., Pezzuto, J.M., Sun, H., and Fong, H.H. Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodonpseudo-irrorata. J. Nat. Prod., 65: 215-217, 2002.
306. Su, B.N., Cuendet, M., Hawthorne, M.E., Kardono, L.B., Riswan, S., Fong, H.H., Mehta, R.G., Pezzuto, J.M., and Kinghorn, A.D. Constituents of the bark and twigs of Artocarpus dadah with Cyclooxygenase inhibitory activity. J. Nat. Prod., 65: 163-169, 2002.
307. Minguzzi, S., Barata, L.E., Shin, Y.G., Jonas, P.F., Chai, H.B., Park, E.J., Pezzuto, J.M., and Cordell, G.A. Cytotoxic withanolides from Acnistus arborescens. Phytochemistry, 59: 635-641, 2002.
308. Zhang, H., Lu, Z., Tan, G.T., Qiu, S., Farnsworth, N.R., Pezzuto, J.M., and Fong, H.H.S. Polyacetyleneginsenoside-Ro, a novel triterpene saponin from Panax ginseng. Tetrahedron Lett., 43: 973-977, 2002.
309. Lee, S.K., Heo, Y.H., Steele, V.E., and Pezzuto, J.M. Induction of apoptosis by 1,4-phenylenebis(methylene)selenocyanate in cultured human colon cancer cells. Anticancer Res., 22: 97-102, 2002.
310. Gu, J.Q., Gills, J.J., Park, E.J., Mata-Greenwood, E., Hawthorne, M.E., Axelrod, F., Chavez, P.I., Fong, H.H., Mehta, R.G., Pezzuto, J.M., and Kinghorn, A.D. Sesquiterpenoids from Tithonia diversifolia with potential cancer chemopreventive activity. J. Nat. Prod., 65: 532-536, 2002.
311. Chavez, D., Cui, B., Chai, H.B., Garcia, R., Mejia, M., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., and Kinghorn, A.D. Reversal of multidrug resistance by tropane alkaloids from the stems of Erythroxylum rotundifolium. J. Nat. Prod., 65: 606-610, 2002.
312. Constantinou, A.I., Lucas, L.M., Lantvit, D., Hawthorne, M., Xu, X., Nho, C.W., Jeffery, E.H., Christov, K., van Breemen, R.B., and Pezzuto, J.M. Soy protein isolate prevents chemically-induced rat mammary tumors. Pharm. Biol., 40: 24-34, 2002.
313. Soejarto, D.D., Pezzuto, J.M., Fong, H.H.S., Tan, G.T., Zhang, H.J., Tamez, P., Aydogmus, Z., Chien, N.Q., Franzblau, S.G., Gyllenhaal, C., Regalado, J.C., Hung, N.V., Hoang, V.D., Hiep, N.T., Xuan, L.T., Hai, N.V., Cuong, N.M., Bich, T.Q., Loc, P.K., Vu, B.M., Southavong, B.H., Sydara, K., Bouamanivong, S., O’Neill, M.J., Lewis, J., and Dietzman, G. An international collaborative program to discover new drugs from tropical biodiversity of Vietnam and Laos. Nat. Prod. Sci., 8: 1-15, 2002.
314. Su, B.-N., Misico, R., Park, E.J., Santarsiero, B.D., Mesecar, A.D., Fong, H.H.S., Pezzuto, J.M., and Kinghorn, A.D. Isolation and characterization of bioactive principles of the leaves and stems of Physalis philadelphica. Tetrahedron, 58: 3453-3466, 2002.
315. Misico, R.I., Song, L.L., Veleiro, A.S., Cirigliano, A.M., Tettamanzi, M.C., Burton, G., Bonetto, G.M., Nicotra, V.E., Silva, G.L., Gil, R.R., Oberti, J.C., Kinghorn, A.D., and Pezzuto, J.M. Induction of Quinone Reductase by Withanolides. J. Nat. Prod., 65: 677-680, 2002.
316. Hedayat, A.S., Yan, B., and Pezzuto, J.M. Optimum designs for estimating EDp based on raw optical density data. J. Stats. Plan. Inference, 104: 161-174, 2002.
317. Rimando, A.M., Cuendet, M., Desmarchelier, C., Mehta, R.G., Pezzuto, J.M., and Duke, S.O. Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol. J. Agric. Food Chem., 50: 3453-3457, 2002.
318. Su, B.-N., Chang, L.C., Park, E.J., Cuendet, M., Santarsiero, B.D., Mesecar, A.D., Mehta, R.G., Fong, H.H.S., Pezzuto, J.M., and Kinghorn, A.D. Bioactive constituents of the seeds of Brucea javanica. Planta Med., 68: 730-733, 2002.
319. Cuendet, M. and Pezzuto J.M. Nonsteroidal anti-inflammatory drugs in cancer treatment. Expert Opin. Ther. Patents, 12: 827-835, 2002.
320. Bhat, K.P. and Pezzuto, J.M. Cancer chemopreventive activity of resveratrol. Ann. NY Acad. Sci., 957: 210-229, 2002.
321. Mi, Q., Lantvit, D., Reyes-Lim, E., Chai, H., Zhao, W., Lee, I.S., Peraza-Sanchez, S., Ngassapa, O., Kardono, L.B., Riswan, S., Hollingshead, M.G., Mayo, J.G., Farnsworth, N.R., Cordell, G.A., Kinghorn, A.D., Pezzuto, J.M. Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests(1). J. Nat. Prod., 65: 842-850, 2002.
322. Blatt, C.T., Chavez, D., Chai, H., Graham, J.G., Cabieses, F., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., and Kinghorn, A.D. Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis. Phytother. Res., 16: 320-325, 2002.
323. Mi, Q., Cui, B., Silva, G.L., Lantvit, D., Lim, E., Chai, H., Hollingshead, M.G., Mayo, J.G., Kinghorn, A.D., and Pezzuto JM. Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay. Cancer Lett., 184: 13-20, 2002.
324. Zhang, H., Qiu, S., Tamez, P., Tan, G.T., Aydogmus, Z., Hung, N.V., Cuong, N.M., Angerhofer, C., Soejarto, D.D., Pezzuto, J.M., and Fong, H.H.S. Antimalarial agents from plants II. Decursivine, a new antimalarial indole alkaloid from Rhaphidophora decursiva. Pharm. Biol., 40: 221-224, 2002.
325. Gu, J.Q., Park, E.J., Totura, S., Riswan, S., Fong, H.H., Pezzuto, J.M., and Kinghorn, A.D. Constituents of the twigs of Hernandia ovigera that inhibit the transformation of JB6 murine epidermal cells. J. Nat. Prod., 65: 1065-1068, 2002.
326. Mi, Q., Cui, B., Chávez, D., Chai, H., Zhu, H., Cordell, G.A., Hedayat, S., Kinghorn, A.D., and Pezzuto, J.M. Characterization of tropane alkaloid aromatic esters that reverse the multidrug-resistance phenotype. Anticancer Res., 22: 1385-1397, 2002.
327. Mehta, R.G. and Pezzuto, J.M. Discovery of cancer preventive agents from natural products: from plants to prevention. Curr. Oncol. Rep., 4: 478-486, 2002.
328. Su, B.-N., Park, E.J., Mbwambo, Z.H., Santarsiero, B.D., Mesecar, A.D., Fong, H.H.S., Pezzuto, J.M., and Kinghorn, A.D. New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes. J. Nat. Prod., 65: 1278-1282, 2002.
329. Christov, K.T., Moon, R.C., Lantvit, D., Boone, C.W., Steele, V.E., Lubet, R.A., Kelloff, G.J., and Pezzuto, J.M. 9-cis-Retinoic acid but not 4-(hydroxyphenyl)ratinamide inhibits prostate intraepithelial neoplasia in Noble rats. Cancer Res., 62: 5178-5182, 2002.
330. Jang, D.S., Park, E.J., Hawthorne, M.E., Vigo, J.S., Graham, J.G., Cabieses, F., Santarsiero, B.D., Mesecar, A.D, Fong, H.H.S., Mehta, R.G., Pezzuto, J.M., and Kinghorn, A.D. Constituents of Musa x paradisiaca Cultivar with the Potential To Induce the Phase II Enzyme, Quinone Reductase. J. Agric. Food Chem., 50: 6330-6334, 2002.
331. Mata-Greenwood, E., Cuendet, M., Sher, D., Gustin, D., Stock, W., and Pezzuto, J.M. Brusatol-mediated induction of leukemic cell differentiation and G1 arrest is associated with down-regulation of c-myc. Leukemia, 16: 2275-2284, 2002.
332. Burdette, J.E., Chen, S., Lu, Z.-Z., Xu, H., White, B., Fabricant, D.S., Liu, J., Fong, H.H.S., Farnsworth, N.R., Constantinou, A.I., van Breemen, R.B., Pezzuto, J.M., and Bolton, J.L. Black Cohosh (Cimicifuga racemosa L.) Protects against menadione-Induced DNA damage through scavenging of reactive oxygen species: Bioassay-directed Iiolation and characterization of Active Principles. J. Agricul. Food Chem., 50: 7022-7028, 2002.
333. Goren, A., Topcu, G., Bilsel, G., Bilsel, M., Aydogmus, Z., and Pezzuto, J.M. The chemical constituents and biological activity of essential oil of Lavandula stoechas ssp. stoechas. Z. Naturforsch, 57: 797-800, 2002.
334. Verotta, L., Guerrini, M., El-Sebakhy, N.A., Assad, A.M., Toaima, S.M., Radwan, M.M., Luo, Y.D., and Pezzuto, J.M. Cycloartane and oleanane saponins from Egyptian Astragalus spp. as modulators of lymphocyte proliferation. Planta Med., 68: 986-994, 2002.
335. Jang, D.S., Cuendet, M., Hawthorne, M.E., Kardono, L.B., Kawanishi, K., Fong, H.H., Mehta, R.G., Pezzuto, J.M., and Kinghorn, A.D. Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2. Phytochemistry, 61: 867-872, 2002.
336. Murillo, G., Salti, G.I., Kosmeder, J.W. 2nd, Pezzuto, J.M., and Mehta, R.G. Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. Eur. J. Cancer, 38: 2446-2454, 2002.
a. Kosmeder, J.W. 2nd and Pezzuto, J.M. Novel plant-derived anticarcinogens. IARC Sci. Publ., 156: 343-347, 2002.
337. Zhang, H.J., Tamez, P.A., Aydogmus, Z., Tan, G.T., Saikawa, Y., Hashimoto, K., Nakata, M., Hung, N.V., Xuan le, T., Cuong, N.M., Soejarto, D.D., Pezzuto, J.M., and Fong, H.H. Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva. Planta Med., 68: 1088-1091, 2002.
338. Su, B.N., Cuendet, M., Farnsworth, N.R., Fong, H.H., Pezzuto, J.M., and Kinghorn, A,D. Activity-guided fractionation of the seeds of Ziziphus jujuba using a cyclooxygenase-2 inhibitory assay. Planta Med., 68: 1125-1128, 2002.
339. Gu, J.-Q., Park, E.J., Vigo, J.S., Graham, J.G., Fong, H.H.S., Pezzuto, J.M., and Kinghorn, A.D. Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme, quinone reductase. J. Nat. Prod., 65: 1616-1620, 2002.
340. Calderon, A.I., Terreaux, C., Schenk, K., Burdette, J.E., Pezzuto, J.M., Gupta, M.P., and Hostettmann, K. Isolation and structure elucidation of an isoflavone and a sesterterpenoic acid from Henriettella fascicularis. J. Nat. Prod., 65: 1749-1753, 2002.
341. Park, E.J. and Pezzuto, J.M. Botanicals in cancer chemoprevention. Cancer Metast. Rev., 21: 231-255, 2002.
342. Xu, H., Fabricant, D.S., Piersen, C.E., Bolton, J.L., Pezzuto, J.M., Fong, H., Totura, S., Farnsworth, N.R., and Constantinou, A.I. A preliminary RAPD-PCR analysis of Cimicifuga species and other botanicals used for women's health. Phytomedicine, 9: 757-762, 2002.
343. Yu, C., Shin, Y.G., Chow, A., Li, Y., Kosmeder, J.W., Lee, Y.S., Hirschelman, W.H., Pezzuto, J.M., Mehta, R.G., and van Breemen, R.B. Human, rat, and mouse metabolism of resveratrol. Pharm. Res., 19: 1907-1914, 2002.
344. Ito, A., Chai, H.B., Lee, D., Kardono, L.B., Riswan, S., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M., and Kinghorn, A.D. Ellagic acid derivatives and cytotoxic cucurbitacins from Elaeocarpus mastersii. Phytochemistry, 61: 171-174, 2002.
345. Kinghorn, A.D., Su, B.-N., Lee, D., Gu, J.-Q., and Pezzuto, J.M. Cancer chemopreventive agents discovered by activity-guided fractionation: An update. Curr. Org. Chem., 7: 213-226, 2003.
346. Hwang, B.Y., Chai, H.B., Kardono, L.B., Riswan, S., Farnsworth, N.R., Cordell, G.A., Pezzuto, J.M. and Kinghorn, A.D. Cytotoxic triterpenes from the twigs of Celtis philippinensis. Phytochemistry, 62: 197-201, 2003.
347. Yu, C., Shin, Y.G., Kosmeder, J.W., Pezzuto, J.M., and van Breemen, R.B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun. Mass Spectrom., 17: 307-313, 2003.
348. Murillo, G., Kosmeder, J.W., Pezzuto, J.M., and Mehta, R.G. Deguelin suppresses the formation of aberrant crypt foci and loss of hexosaminidase activity in the colon of CF-1 mice. Intl. J. Cancer, 104: 7-11, 2003.
349. Duncan, C.J., Cuendet, M., Fronczek, F.R., Pezzuto, J.M., Mehta, R.G., Hamann, M.T., and Ross, S.A. Chemical and biological investigation of the fungus Pulveroboletus ravenelii. J. Nat. Prod., 66: 103-107, 2003.
350. Zhang, H.-J., Tan, G.T., Hoang, V.D., Hung, N.V., Cuong, N.M., Soejarto, D.D., Pezzuto, J.M., and Fong, H.H.S. Natural anit-HIV agents. Part 3: Litseaverticillols A-H, novel sesquiterpenes from Litsea verticillata. Tetrahedron, 59: 141-148, 2003.