Department of Pharmaceutical Sciences

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Ingo Koomoa-Lange, Ph.D.


The laboratory’s research focuses on understanding how divalent cation signaling promotes pathophysiological processes that are present in the malignant progression of pediatric cancers as well as during acquisition of drug resistance. In particular the research focuses on understanding how these signals are delivered across organelles and plasma membranes through divalent cation conducting channels as well as membrane potential modulating channels and regulators.

The lab utilized a unique approach by combining molecular, biochemical, biophysical and high-content imaging and genomic analysis. Further, the laboratory is interested in how innate immune cells promote or suppress malignant progression of different pediatric cancers.


  • Dipl. rer. nat., Biology/Biochemistry, University of Erlangen-Nuremberg, Germany
  • Ph.D., Immunology/Physiology/Biophysics
  • Postdoctoral Research in Immunology/Biophysics at New York University Medical Center, NY and Cancer Biology at the University of Hawaii Cancer Center and DKICP, UH Hilo

Classes and Courses

  • PHPS 503 Pharmaceutical Calculations
  • PHPP 515 Integrated Therapeutics I
  • PHPS 511 Pharmacokinetics

Selected Presentations and/or Publications

  • International Journal of Oncology, 2016, Feb 3. doi: 10.3892/ijo.2016.3373
  • Journal of Pharma and Pharmaceutical Sciences, 2015, Vol: 1, Issue: 1
  • Mucosal Immunology,2016 Jul 20.doi: 10.1038/mi.2016.60
  • Phytotherapy Research2015 Apr;29(4):582-90
  • Mol Biol., 2014 Jan 23;426(2):332-46.

Active Grants

  • Alex’s Lemonade Stand Foundation Young Investigator Award